Alcet® Tablet is a formulation containing Levocetirizine Dihydrochloride. Levocetirizine is the active (levo) isomer of cetirizine, known for being a highly effective and well-tolerated non-sedating antihistamine with potent anti-allergic properties. It has a two-fold higher affinity for H1 receptors compared to cetirizine. Levocetirizine acts rapidly and has a long-lasting effect, enabling once-daily administration.

Each film-coated tablet contains Levocetirizine Dihydrochloride INN 5 mg.

Levocetirizine is indicated for the treatment of symptoms associated with allergic conditions, including:
Perennial allergic rhinitis
Seasonal allergic rhinitis
Chronic idiopathic urticaria

Adults and children over 6 years of age: One Alcet® tablet once daily.

For moderate renal impairment (Creatinine Clearance 30–49 ml/min): One Alcet® tablet every two days.

For severe renal impairment (Creatinine Clearance <30 ml/min): The dosing interval should be increased to every three days.

Patients with end-stage renal disease (Creatinine Clearance <10 ml/min): Do not administer Alcet®.

The tablet should be swallowed whole with liquid and may be taken with or without food.

Levocetirizine is generally well-tolerated. However, rare side effects include:
Headache
Dry mouth
Fatigue
Skin rash
Contraindications

Hypersensitivity to levocetirizine, cetirizine, or its parent compound hydroxyzine. Severe renal impairment (Creatinine Clearance <10 ml/min).

Pregnancy:

The safety of levocetirizine in pregnancy has not been established. Use only if the potential benefits to the mother outweigh any risks to the fetus.

Lactation:

Levocetirizine is excreted in breast milk. Therefore, its use is not recommended for nursing mothers.

Geriatric Use:

Dose adjustments may be necessary in elderly patients with impaired renal function.

Hepatic Impairment:

No dosage adjustment is required for hepatic impairment.

Pediatric Use:

Not recommended for use in children under 6 years of age.

Levocetirizine is not known to interact with other drugs.

No clinically significant adverse effects have been reported in cases of overdose.
In the event of an overdose, symptomatic and supportive treatment is recommended.

Store in a cool, dry place below 30°C.

Protect from light.

Alcet® Tablet: Box containing 10 x 10 tablets in blister packaging.

Medicine: Keep out of reach of children.