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Clindamycin is a lincosamide antibiotic with a primarily bacteriostatic action against Gram-positive aerobes and a wide range of anaerobic bacteria. Lincosamides such as Clindamycin bind to the 50S subunit of the bacterial ribosome similarly to Macrolides such as Erythromycin and inhibit the early stages of protein synthesis. The action of Clindamycin is predominantly bacteriostatic although high concentrations may be slowly bactericidal against sensitive strains.
Clindamycin hydrochloride has been shown to be effective in the treatment of the following infections when caused by susceptible anaerobic bacteria or susceptible strains of gram positive bacteria such as streptococci, staphylococci and pneumococci : l Upper respiratory infections, l Lower respiratory infections, l Skin and soft tissue infections, l Bone and joint infections, l Pelvic infections, l Intra-abdominal infections, l Septicemia and endocarditis, l Dental infections. As an alternative therapy when used in combination with quinine or amodiaquine for the treatment of multi-drug resistant Plasmodium falciporum infection.
Cleocin® cream is indicated in the treatment of bacterial vaginosis. Cleocin® cream can be used to treat non-pregnant women and pregnant women during the second and third trimester.
Cleocin® 300 mg capsule: Each box contains 28 capsules in Alu-Alu blister pack.
Cleocin® Cream: Each tube contains 20 gm of Clindamycin cream.