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Cephradine is a cephalosporin antibiotic with broad spectrum bactericidal activity against both gram-positive and gram-negative bacteria. It is also highly active against most strains of penicillinase producing staphylococci. The organisms sensitive to cephradine are: Gram-positive: Staphylococci (both penicillin sensitive and resistant strains), Streptococci including both Streptococcus pyogenes (beta haemolytic) and group D Streptococci (enterococci) and Streptoccoccus pneumoniae. Gram negative: E. coli, Klebsiella, P. mirabilis, Hemophillus influenzae, Shigella spp. (including Salmonella typhi) and Neisseria spp. Enterococci (S. faecalis) and many strains of E. coli and Staphylococcus aureus are also susceptible. Rocef® (Cephradine) is rapidly absorbed from the gastrointestinal tract. Absorption is delayed by presence of food although the total amount absorbed is not appreciably altered.
Cephradine is used in the treatment of infections caused by sensitive organisms.
Upper respiratory tract infections: Pharyngitis, sinusitis, otitis media, tonsillitis, laryngotracheo-bronchitis.
Lower respiratory tract infections: Acute and chronic bronchitis, lobar and bronchopneumonia.
Urinary tract infections: Cystitis, urethritis, pyelonephritis.
Skin and soft tissue infections: Abscess, cellulitis, furunculosis, impetigo.
Gastrointestinal tract infections: Bacillary dysentary, enteritis, peritonitis.
Bone & joint infection.
Surgical prophyaxis: It is also used in perioperative prophylactic administration (pre-operatively, intra-operatively & post-operatively). In cesarean section, intra-operative (after clamping the umbilical cord) and post-operative use may reduce the incidence of certain post-operative infection.
Rocef® 250 Capsule: Box containing 5 x 6 capsules in Alu-Alu strip pack
Rocef® 500 Capsule: Box containing 4 x 6 capsules in Alu-Alu strip pack
Rocef® Dry Syrup: Bottle containing Rocef® dry powder to reconstitute 100 ml syrup.
Rocef® Forte Dry Syrup: Bottle containing Rocef® dry powder to reconstitute 100 ml syrup.