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Omeprazole inhibits secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium adenosine triphosphatase (H+/K+ATPase), the proton pump of the gastric parietal cell oral dosing with Opal®, produces inhibition of gastric acid secretion within 1-2 hours of the first dose. The maximum effect is achieved within 4 days of starting of treatment after which the degree of acid inhibition remains constant.
For the treatment of gastro-oesophageal reflux disease, peptic ulcer disease, for the eradication of Helicobacter pylori in peptic ulceration (triple therapy), acid related dyspepsia, NSAID associated duodenal or gastric ulcer and gastroduodenal erosions, Zollinger-Ellison Syndrome.
Opal® 20 mg capsules: Box containing 10x6’s capsules in Alu-Alu blister pack.
Opal® 40 mg capsules: Box containing 8x4’s capsules in Alu-Alu blister pack.
Opal® 40 mg i.v. injection: Each combipack contains 1 vial of 40 mg of Omeprazole, 1 ampoule of 10 ml sterile water for injection and 1 sterile disposable syringe 10 ml.