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Cisplatin is a heavy metal complex containing a central platinum atom surrounded by two chlorine and two ammonia molecules. Cisplatin occurs as a fine yellow powder which decomposes at 270 ºC. Cisplatin is soluble in water (0.253 g/100 g at 25 ºC).
Cisplatin is indicated as palliative therapy, to be employed in addition to other modalities, or in established combination therapy with other chemotherapeutic agents in the following:
• Metastatic Testicular Tumors: In patients who have already received appropriate surgical and/or radiotherapeutic and/or chemotherapeutic procedures.
• Metastatic Ovarian Tumors: As secondary therapy in patients refractory to standard chemotherapy.
• Advanced Bladder Cancer- As a single agent for patients with transitional cell bladder cancer.
Cisplat®-10 concentrated solution for i.v. infusion: 1 vial of 10 ml concentrated solution for infusion contains 10 mg cisplatin BP.
Cisplat®-50 concentrated solution for i.v. infusion: 1 vial of 50 ml concentrated solution for infusion contains 50 mg cisplatin BP.